Is now a good time to defoliate?

the big ass leaves feed your Plant... i wont take any leave away now, because she needs it. You can top her ;to open the canopy. And later in week 2 of flower you can take away blocking leaves. Iam no frind of defoiliation is classic way. iam a big friend of taking away some disturbing leaves, cleaning up the bottom area of the Plant This big leaves feed her and she will get stunted if you take away those. later if shes bigger she dont have that big need to keep them- you can look into my diary " organic bananas" that plant developed biiig leaves too,,, and i let her doing it... other growers took them away,,, and the plant had to work for 10 days to regrow another nutrientleave

You have plenty of light getting into your girls, wait until they have many leaves before removing the fan leaves. Once you switch to 12 12 then the 2 weeks of stretch, then remove your big sun blocking leaves. Cheers