AsNoriuanswered grow question 4 months ago there is way more ways to manipulate plant, than pure harm and loosing growing time. I would recomend you to check LST, supercroping, scrog as techniques. Toping, mainlining is waste of time in mind mind, but many growers do it. read articles, why and when, there is no simple answer to it. even first top some people do on 4 or 5 node, some on third, some do on 6th or seven, all depends what you want to achieve and how you plan your future manipulation ...