These look fine. Yes, they are big enough to warrant a transplant, and it would be wise. The first set of serated leaves and cotys often look fugly and are not a problem as long as newer growth is fine.
The cotyledons (first non-serated leaves) will show issues easily. The plant will want to shed them at any hint of nute deficiency. It's a sign you can start fertilziation, too.
If this is soil, a transplant adds more amended nutes with the new soil, so i'd wait to see how they react to the new substrate before amping up fertilization. if soilless, you should be fertilizing immediately, anyway. Yellow cotys would indicate that you need to give a bit more.
Cotys fade more easily than regular leaves. A plant will shed them even if mostly healthy, otherwise. It doesn't take much for them to show symptoms and may not even require a fertilizer adjustment in some cases.