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@CalGonJim
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8/4 130am. MONDAY. just AN from now on, no more aminos they will just ad N at this point and counter flowering. 🚨🚨8/4 12:30pm !!! FOR HUMANS!!!!!!🚨🚨👨‍🔬Combining **L-glutamine**, **proline**, **essential amino acids (EAAs)**, **glycine**, and **trimethylglycine (TMG)** in your supplement regimen, as seen in the nutrient mix you described for your cannabis grow, can have significant effects on human health, particularly given your positive experience with methylene blue (“I feel great after I take it”). Since you’re asking about the benefits for yourself (not plants), I’ll focus on how these compounds may contribute to your well-being, their synergistic effects, and how they might align with the energy and mood boost you’ve reported. I’ll also consider the context of your previous questions, including the nitric oxide (NO) precursors and methylene blue, to provide a comprehensive picture. The response will be concise yet thorough, addressing mechanisms, benefits, and potential considerations. ### Overview of Each Component and Their Benefits for Humans 1. **L-Glutamine (500 mg in your mix)**: - **Role**: A conditionally essential amino acid, critical for gut health, immune function, and muscle recovery. - **Benefits**: - **Gut Health**: Supports intestinal lining repair, reducing leaky gut and improving digestion, which can enhance overall well-being and energy. - **Immune Support**: Fuels immune cells (e.g., lymphocytes), boosting resilience, especially during stress or illness. - **Muscle Recovery**: Reduces muscle soreness and supports protein synthesis, beneficial if you exercise or are physically active. - **Brain Health**: Serves as a precursor to neurotransmitters like glutamate, potentially improving focus and mood. - **Relevance to You**: The energy and mood boost you feel may partly stem from glutamine’s role in reducing inflammation and supporting brain function. 2. **Proline (100 mg in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, tissue repair, and antioxidant defense. - **Benefits**: - **Joint and Skin Health**: Promotes collagen production, supporting joint flexibility, skin elasticity, and connective tissue repair. - **Cardiovascular Health**: Supports arterial wall integrity, potentially complementing the NO precursors in your mix (L-arginine, L-citrulline). - **Stress Resistance**: Acts as an osmoprotectant, helping cells manage oxidative stress, which may contribute to your “feeling great.” - **Relevance to You**: Proline’s low dose may subtly support tissue health and stress resilience, enhancing your overall vitality. 3. **Essential Amino Acids (EAAs, 300 mg in your mix)**: - **Role**: EAAs (e.g., leucine, lysine, methionine) are amino acids the body cannot synthesize, essential for protein synthesis and metabolic functions. - **Benefits**: - **Muscle Maintenance**: Stimulates muscle protein synthesis, aiding recovery and preventing muscle loss, especially during exercise or aging. - **Energy and Mood**: EAAs like leucine support energy metabolism, while tryptophan and phenylalanine are precursors to serotonin and dopamine, potentially boosting mood. - **Metabolic Health**: Supports insulin sensitivity and nutrient metabolism, contributing to sustained energy. - **Relevance to You**: EAAs may enhance your energy and mood by supporting muscle recovery and neurotransmitter production, aligning with your positive response to the mix. 4. **Glycine (1 g in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, neurotransmitter regulation, and detoxification. - **Benefits**: - **Sleep and Mood**: Acts as an inhibitory neurotransmitter, promoting relaxation and improving sleep quality, which can enhance mood and energy. - **Cognitive Health**: Supports NMDA receptor function, potentially improving memory and focus. - **Collagen and Joint Health**: Like proline, supports connective tissue and skin health. - **Detoxification**: Aids in glutathione production, reducing oxidative stress and supporting liver function. - **Relevance to You**: Glycine’s calming effects and antioxidant support may contribute significantly to your “feeling great,” especially if you experience better sleep or reduced stress. 5. **Trimethylglycine (TMG, 1 g in your mix)**: - **Role**: Also known as betaine, TMG is a methyl donor involved in homocysteine metabolism and cellular protection. - **Benefits**: - **Cardiovascular Health**: Lowers homocysteine levels, reducing heart disease risk, and may synergize with NO precursors for better blood flow. - **Exercise Performance**: Enhances hydration and muscle endurance, potentially improving physical energy. - **Liver Health**: Supports fat metabolism and detoxification, reducing liver stress. - **Mood and Stress**: Methylation supports neurotransmitter synthesis, potentially boosting mood. - **Relevance to You**: TMG’s role in energy metabolism and methylation may amplify the mood and energy benefits you’re experiencing. ### Synergistic Benefits of the Combination The combination of L-glutamine, proline, EAAs, glycine, and TMG, alongside the NO precursors (L-arginine, L-citrulline, etc.) and methylene blue from your mix, creates a synergistic effect that likely explains why you “feel great”: 1. **Enhanced Energy and Recovery**: - **Glutamine, EAAs, and TMG**: Support muscle protein synthesis, energy metabolism, and recovery, reducing fatigue and boosting physical vitality. Beta-alanine (from the NO capsule) buffers lactic acid, enhancing exercise endurance. - **NO Precursors**: L-arginine and L-citrulline increase NO production, improving blood flow and oxygen delivery to muscles and brain, enhancing energy and focus. - **Methylene Blue**: As you noted, methylene blue enhances mitochondrial efficiency, boosting ATP production, which complements the energy-supporting effects of glutamine, EAAs, and TMG. 2. **Mood and Cognitive Boost**: - **Glycine and EAAs**: Glycine promotes relaxation and sleep, while EAAs (e.g., tryptophan, phenylalanine) support serotonin and dopamine production, enhancing mood and mental clarity. - **TMG**: As a methyl donor, supports neurotransmitter synthesis and reduces homocysteine, which is linked to mood disorders. - **Methylene Blue**: Its mild MAO inhibition may increase serotonin and dopamine levels, amplifying the mood benefits you’re experiencing. 3. **Stress Reduction and Resilience**: - **Proline, Glutamine, and Glycine**: Act as antioxidants and osmoprotectants, reducing oxidative stress and supporting cellular health under physical or mental stress. - **TMG**: Enhances methylation, supporting stress resilience and detoxification. - **Methylene Blue**: Its antioxidant properties may reduce cellular stress, complementing the other compounds. 4. **Cardiovascular and Tissue Health**: - **Proline, Glycine, and TMG**: Support collagen synthesis and cardiovascular health, improving joint, skin, and arterial function. - **NO Precursors**: Enhance vasodilation, improving blood flow and nutrient delivery, which may contribute to your overall sense of well-being. ### Why You Feel Great Your positive response (“I feel great”) likely stems from the combined effects of: - **Mitochondrial and Energy Boost**: Methylene blue and glutamine enhance ATP production and energy metabolism, giving you a physical and mental lift. - **Neurotransmitter Support**: Glycine, EAAs, TMG, and methylene blue support serotonin, dopamine, and GABA activity, improving mood, focus, and relaxation. - **Reduced Stress**: Proline, glutamine, and TMG combat oxidative stress and support recovery, reducing fatigue and enhancing resilience. - **Improved Blood Flow**: NO precursors increase circulation, delivering more oxygen and nutrients, which may enhance energy and cognitive clarity. The doses in your mix (500 mg glutamine, 100 mg proline, 300 mg EAAs, 1 g glycine, 1 g TMG) are within typical supplemental ranges, suggesting a balanced approach that avoids overload while providing cumulative benefits. ### Considerations and Precautions 1. **Dosage Safety**: - Your doses are moderate and generally safe for most adults, but long-term high doses of TMG (1 g daily) or glutamine (500 mg daily) may stress the liver or kidneys in sensitive individuals. Typical supplemental doses are 500–3,000 mg for TMG and 5–10 g for glutamine, so you’re on the lower end. - Methylene blue (2 drops of 5% solution ≈ 5 mg) is a low dose, but its long-term use lacks extensive human studies. Monitor for side effects like nausea or dizziness. 2. **Interactions**: - **Methylene Blue and SSRIs**: Methylene blue is a mild MAO inhibitor and can cause serotonin syndrome if combined with SSRIs or other serotonergic drugs. Consult a doctor if you’re on such medications. - **NO Precursors**: L-arginine and L-citrulline may lower blood pressure, so monitor if you have hypotension or take related medications. - **TMG and Methylation**: High TMG doses may overstimulate methylation, potentially causing anxiety in some individuals. Your 1 g dose is moderate but worth monitoring. 3. **Individual Response**: - Your positive response suggests your body responds well to this mix, possibly due to baseline deficiencies (e.g., in glycine or glutamine) or high metabolic demands (e.g., from exercise or stress). Genetic factors affecting methylation (e.g., MTHFR mutations) may make TMG particularly effective for you. 4. **Nutrient Timing**: - Taking this mix in the morning (as implied by 2:47 AM) aligns with boosting energy and focus for the day. However, glycine’s calming effects might be better utilized at night for sleep support. Consider splitting doses (e.g., glycine in the evening, others in the morning). ### Recommendations - **Optimize Timing**: Take glutamine, EAAs, and TMG in the morning for energy and recovery, and glycine in the evening for relaxation and sleep. Proline can be taken anytime due to its structural role. - **Monitor Effects**: Track specific benefits (e.g., energy, mood, sleep, exercise recovery) to identify which compounds drive your “feeling great.” If methylene blue is key, its mitochondrial and mood effects may be central. - **Hydration and Diet**: Ensure adequate hydration and a balanced diet, as amino acids and TMG increase metabolic demands. Pair with B vitamins (especially B6, B12, folate) to support methylation and amino acid metabolism. - **Consult a Professional**: Discuss this regimen with a doctor or nutritionist, especially regarding methylene blue and NO precursors, to rule out interactions or contraindications (e.g., G6PD deficiency for methylene blue). - **Adjust Doses if Needed**: If you notice side effects (e.g., jitteriness from TMG, GI upset from glutamine), reduce doses (e.g., 500 mg TMG, 250 mg glutamine) and reassess. ### Conclusion The combination of L-glutamine, proline, EAAs, glycine, and TMG likely contributes to your feeling great by boosting energy (via mitochondrial support and muscle recovery), enhancing mood (through neurotransmitter production), reducing stress (via antioxidant and osmoprotectant effects), and supporting cardiovascular and tissue health. Methylene blue and NO precursors from your mix amplify these benefits by improving mitochondrial function and blood flow. Your moderate doses are generally safe, but careful monitoring and medical consultation are advised, especially for methylene blue. If you’d like, I can search for recent studies or X posts on these supplements for human use, or tailor a dosing schedule based on your goals (e.g., energy, mood, recovery). Let me know how you’d like to proceed!🚨👨‍🔬. 8/4 1230pm. 8/5 12:50am HEY HARRISON SMITH, HARVEY WALL BANGER, GET IT?...IM SO GOOD. ANYHOW....FLUSH TODAY, FLORAKLEEN 5ML PER GALLON ALL OF THEM..... NO DONT PILLAGE ME AND IM LIKE NO! IM PILLAGING EVERYBODY, YOU INCLUDED. 8/5 3:51 AM I mixed up floor clean 5 mL per gallon doing bubbles first and then goats and the other girl next to it👍 8/5 7:10 AM I’ve been doing this since five and I can’t believe how high my EC was. It was off the chart like 6000 7000 so I had to do the flush. I’m never really bothered to do this before. I’m sure it’s gonna be a lot better. One of my last grows. The leaves were so full of garbage. Basically my weed smell like a hamburger so not exactly good but I’ll save it for people. I don’t like👍. Sometimes it doesn’t remember a whole paragraph. I just fucking typed piece of shit took me six hours to do four fucking plants.🤣💥💥💥 8/6 408am. The colas on the oldest of the 3 are AMAZING!!!! they are all small but MIGHTY!! 2 cola grows in 1 gallon seem to be about right. I will probably get 4oz dry from EACH!! That is really acceptable!!! For a home micro- grow where the goal is ALSO to grow as many different kinds, to get more seeds, which keeps the seed companies coming up with new strains!!!! The 1 gallon plastic pots are light, small bags of Soil Sunrise from online is easy to store, CLEAN! the bags of dirt it comes in are strong, and easy to wipe up when done. The 8qt fills several pots I also mix in about 4 8oz cups of Perlite per container to stretch the dirt out a bit. Soil Sunrise delivered by amazon is the only dirt that did NOT have bugs...I used to order HUGE bags of FF delivered from outdoor garden centers all over the country ...the bug infested HORROR, never again!!! 8/6 418am Also my body is starting to fail, I can feel it. If there is any discomfort there will be no more updates. thats life. doesnt it go by in a blink? I think to myself what a bullshit goblin & demon infested shithole of a world, cant dies soon enough. And death to the shitters of 1978!!!😡 Did you ever hear about the Tragedy of Darth Arnie and Christine? He's more Chrysler 1958 Plymouth Fury than man now...maybe I got the movies mixed up again....idk....
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Very happy with the result. Very strong and high quality with great bag appeal.
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@Roberts
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So I switched to Athena nutrition 48 hours ago. As you can see the plant was not liking the Xpert Nutrients solution mix. I honestly don't think the mixture was strong enough. Regardless I had to switch to save the plants. I will try the Xpert Nutrients again on another grow. She did start showing more life since the switch. Hopefully she bounces back fast. Thank you Medic Grow, Xpert nutrients, Athena, and Fast Buds. 🤜🏻🤛🏻🌱🌱🌱
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@maxwell
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Week 5 folks 💪 Time for Defolation and I put a net inside the tent and also a 600watt hdl lamp. They only got some plain water! I think they look great this time! I got a present from a friend 2 Power Plant clones, they have no vegetation time but I thing they doing well with the 12/12 light schedule! Till next week community
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My first Grow with random cuttings. I found growdiaries after the Haverest.
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sour 76 stopped stretching at 22, 23 and 24 inches. yeti number 4 stopped at 32 inches, while yeti 3 stretches another few inches as sour "tower" begins stacking and starting to trich up
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This is the week 2! Well, the plant looks really healthy, and she kept growing up, straight to the light! Good to see that even after the strange beginning, with the stem crooked, she recover her path! This week, I'm also planning to start feeding them with some NPK. Just need to read a little bit more about it and buy nutrients. Probably I'll try Canna stuff. Anyone know if it's good?
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@NuttyYeti
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She seems ready! Smells so good like pineapple and diesel but also fruit punch. I'm excited to try it! 💚🌱✌️
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Time to Acclimate! Small dose of nutrients & LEDs will go from 50 -75% over the course of the next week. ~~~~~~~~~~ Roots look good, transplanted and ready to explode through veg! Nutrients will be on next week's post - the above is what I use to acclimate.
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Der Stretch neigt sich dem Ende zu und das Netz wurde entfernt – beide Pflanzen stehen jetzt stabil und frei im Raum. Nach dem Lösen des ScroG zeigt sich deutlich, wie kräftig die Struktur aufgebaut wurde: dicke Stämme, starke Seitentriebe und ein gleichmäßiges, volles Blätterdach. 24K Gold reagiert mit einem beeindruckenden Stretch-Finish. Ihre Haupttriebe sind kräftig und leicht über dem Restniveau, perfekt verteilt für maximale Lichtausbeute. Die ersten Blütenansätze sind klar zu erkennen – kleine weiße Härchen schießen an allen Spitzen hervor. Gelato 33 bleibt etwas gedrungener, aber sehr kompakt und buschig. Ihre Top-Sites sind gleichmäßig verteilt und zeigen ebenfalls die ersten Pistillen. Das entfernte Netz hat ihr Raum gegeben, sich frei nach oben zu entfalten. Eine gezielte Entlaubung wurde vorgenommen, um die unteren Bereiche zu öffnen und die Luftzirkulation zu optimieren. Das Laub ist tiefgrün und gesund – keine Mängel oder Verbrennungen sichtbar. Düngung & Werte: • 💧 Canna Coco A + B → 6 ml/l • 📈 EC: 1.6  pH: 5.8 • 🌡️ Temperatur: 25–26 °C • 💧 Luftfeuchtigkeit: 50–55 % • 💨 Umluft: stark & konstant • 💦 Tropfbewässerung mit kontrolliertem Drain Der Fokus liegt nun voll auf Blütenbildung – die Pflanzen stehen stabil, haben den Stretch abgeschlossen und beginnen mit sichtbarem Blütenaufbau. Ein sehr kräftiger Start in die Hauptblütephase!
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@Rollerboy
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Got my tea brewing station up and running, my first brew did not go as planned, i fucked it up and added bud candy, later i asked Google AI and it told me that was a no - go ! The second brew i followed the guide lines, added 15 grams pr. plant of P-K booster compost tea, then 5ml of Orgatrex, let it bubble and brew for about 36 hours, then added a few grams of Bactrex right before watering in. I plan on using Bio tabs for the flowering from now on, except for the Plagron Supermix/Bat Guano/Root Explosion i´m adding to the medium. Also added a Hydrone 5 de-humidifier to bring the high humidity down. It did not fit the opening on my tent perfectly ! The plants did not like the warm and dry air the de-humidifier created in the bottom part of the tent, many of the bottom leaf´s withered and dropped ! Well it has to work, i need that Hydrone 5 to keep my humidity down, so i don´t get bud rot again like i did on the previous grow, with the Barneys farm O.G. Kush. From week 6 of flower i will feed them bio PK 5-8 from Bio tabs, will give the plants 3ml 3 times a week, i will also add Guanokalong Bat Guano extract at 10ml/1Liter of solution, i will feed them this untill half of week 7, then plain PH´d water till harvest.
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@Regenwurm
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Die 12 Blütewoche ist erfolgreich abgeschlossen! Tage der Wachstumsphase = 32 Tage. Tage der Blütephase = 84 Tage Wachstum h in Blütewoche 9= 0 cm Blütenbildung: sehr Hoch Die Blütenkelche sind Mitten in der Produktion und verfärben sich. Die Trichome sind bei beiden ladies im gesamten trüb. Heißt, der Harvest Day nähert sich. Ich denke 14-18 Tage 👌 In dieser Woche den Ladies einige Blätter abgenommen das in der Endphase das Licht die buds erreicht. Der Wasserbedarf der Pflanze ist gleichbleibend moderat. Diese Woche 4 Tage von 7 gegossen Mutation 1= strähnige Blüten (wie bei der Dr. Greenspoon öfter mal vorkommt) Mutation 2 = Gigantismus (doppelt so viele DNA Ketten wie regulär) Mutation 3 = Sekundäre Blüten an Blättern 2 mal in dieser Woche mit Purolyt Mischung 1:25 besprüht Lichtstärke: 87 % Lichtabstand: 36 cm Std Tag/Nacht: 12/12 Temperatur Tag: ca. 24-25 Grad RLF Tag: 50-55% Temperatur Nacht: 20-21 grad RLF Nacht: ca. 50 % VPD Wert: ca. 1.2 PH Wert Wasser/Düngelösung: 6,4 EC Wert: 1,0 Ventilator Oszillation: Stufe 2 Befeuchter: aus Entfeuchter: mit Steuerung an Zusätzlicher Entfeuchter: 1 Stk außerhalb vom Zelt im Raum Bewässerung: 1* Wasser PH 6,6 EC 0,1/ 3 * bewässert mit Dünger mit den o.g. Mengen Purolyt Besprühung: 2 mal Controlling: Grow Control Dünger: Greenbuzz Nutrients Licht: Pro Emit Vollspektrum Abluft: EC Carbon Active 750 m3 gesteuert/PrimaKlima 480m3 https://greenbuzznutrients.com/de/ Danke an Greenbuzz Ihr bekommt 25 % Rabatt bei der Nutzung des Codes auf der GB Homepage https://greenbuzzliquids.com/de/shop/ Code: GD42025 (Mindestbestellwert 75€)
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@Smokwiri
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Welcome to my bubble gum xl diary Genetics: Royal Queen seeds Developing is good, looks nice and healthy. Topped/fimmed 4 side branches, Lets see how this one comes out, thinking about putting her on 12/12 somewhere in the coming week, maybe next week
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Week 5 successful 🌱 time for flower ma friends and time for the bloom nutrients.
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Top Dressed with my dry amendments and topped 3 nodes down with of all branches. Trying to really bush it out under a scrog. The nutrients kicked in within the week on the Acapulco Gold. - Changed the light from about 15% to about 35% at the same height on the ES180 - By using the mixture of Bio Tone and Earth dust I am introducing symbiotic microorganisms into the soil, mostly fungus. From what I understand these mycelium help the plant uptake the food grow healthier roots. - My goal is to use the increased nutrient availability to help the plants handle more light intensity and meet it vigorous growth. -Turned both fans on for stem strength -
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day 49 just pure water phed down. it is day 51, morning before lights on, I might chop today. I use a zero water filter pitcher got off walmart. My humidifier is only a sonic wave. If you use regular tap water it will get gunky in a sonic humidifier. If you have a heat humidifier that boils the water the mist should be clean. These are the 2 types of water humidifiers. Researching best water filters this "zero water" also comes with a free ppm meter! yay! Other water pitcher brands; the water still has ppm. So water misted will still have ppm contamination. You can easily used distilled water only, and reverse osmosis. I just fill a 4gal office water jug with the pitcher and fill my humidifier when needed. I do not use a humidifier in my entire grow up to this point when I chop, I need the perfect rh or this whole effort can fail. growing up to this point only requires 20% effort, chopping now for the 2 weeks dry is this 80% of crucial determination, succeed. A lot of tasks are required today for a clean chop. I feel confident, observed my cross seeds with pink paradise and one with a slightly open caylex looks dark enough for successful germination. I figured 8-16 seeds may be created, 3-4 buds were potentially pollinated. Many growers don't understand when creating genetics with female/female there is a slight chance of herm. You lose 50% of your genetic function. Just water last 2 days, no humic no folvic, 1st time entire grow ha! There is a lot of cleaning to do, remove the trees, clean the entire tent and environment with bleach water, hacksaw. I am very proud of my grow. I have sampled 3 of the strains, dr. thunder legit made my lips numb but it could have just been the terps removing my skin cells from the sticky filter, no lie. This is my best grow to date. I did this for you, and to document hype or not under the best conditions I could give my plants, full max potential, although I wish I had more lights, I am not looking for industrial lol, this is how I grow. Learn a lot on youtube and podcasts there is many good content and I may dab into it. You can have a room full of growers and you have 1 seed in your hand, they will all tell you that their way is correct ;) and the best way. Oreo is stinky AF, Bridal is just amazing glad its massive, just not into sativa but the test seemed slight sativa with majority indica, pink untested, dr, thunder just a lip numming plant aha, its very nice, all 4 amazing appeal like advertised, and excited for next run. Either crosses from this or other copycat genetics. I will give you beautiful glamout shots today, the sizes of the plants, My guesstimate bridal 1lb, thunder 1lb, pink, 0.4lb, bridal 0.5, I am ambitious off 640w lm301h, and 4x 20w blurples daisy chained. day 51 4 chopped see you in a few weeks :D
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Another one down, now the tent can flourish. Already going into third week on the next flower cycle. Going to try a dry trim on this one. So far I've been doing wet trims, but I have more space this dry cycle. I've had chocolope a few times before, a few different phenotype expressions from the original seeds. I'll be curious to see if this is just like those previous chocs or if I will be able to pick out notes of whatever it crossed with. It definitely grew like chocolope I've grown in the past, very stretchy, long stretch time, genetically foxtailly. 8/12 getting ready to do a little test press on some larfy nugs that should be a bit dryer than the big nugs. In the bag, it smells just like Nam wah, but the plant 100% had the chocolope structure, except the buds were smaller than a choc for sure. I kind of attributed that to having an ec issue early flower, but maybe it was the Nam wah influence. Pretty crazy how the genes crossed like that. Wow. It got pretty warm here and we're letting the house breathe, so the tent is actually warmer during lights out daytime, than it is during lights out night. I like it, seems to make them grow faster and could potentially shorten flower time.