You should use it through vegetative phase and first weeks of flowering. It can be a good idea to drop the strenght of the silica to 65% of the full dose at around halfway of flowering. For the last 2-3 weeks, there is no need/ real practical use for silica additives.
Also, when adding to a bigger tank:
1) mix your silica with 3-4 litres (1 us gal) of water
2) add all the other nutrients and whatnots to tank, then
3) add the water-silica mix slowly while mixing (yeah, you should spend hours here, I don't, got shits to do)