a blotch or 3 on an older, lower leaf... i'd wait to see more before reacting. the plant looks healthy and this looks very isolated. plus, only a few things leave that sort of symtom and the area of plant and the type of things that cuase it are unusual or doesn't fit location on plant. (light burn / boron deficiency)
as leaves age or get shielded from light more, they change and sometimes get a bit ugly.. maybe even see them get a little mottled. older leaves don't photosynthesize as efficiently at some point but still more than any other green surface on the plant.
Ensure your pH is proper -- what you give and slap a ph strip into the runoff too... runoff will never be accurate, but it'll give a gist. (it's a weighted average of what was in teh soil and what you added plus some other dynamics that cloud the reading too... so as longn as not significantly different, no worries)...