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Had to do another defoliation just after defoliating in week 4...they reset large leaves within a week...i also laid/spread the canopy a bit more to allow airflow and light...i most likely will Defoliate again once more before flowering then not until week 3 flowering, and only lightly at that point..plants don't reproduce leaves after week 3 an will mostly start focusing on bud development..removing to many leaves at this stage will reduce yeilds and plants ability to convert light into energy..