Sour Tangie Forbidden Fruit Cake

I'm struggling to solve my problem this grow. I added more perlite than I have the last 2 grows and have been experimenting with bottom watering. At first I thought nutrient deficiency. So I added some grow nutes. Didn't really help stop the lower leaves from yellowing. The growth is also slow. I am gonna go back to top watering and to start I will be flushing all of them thoroughly to make sure it's not a lockout. My last two grows I didn't see any yellowing until partway into flowering. The sex has shown on 4 plants. All female by some miracle. Have one straggler. Probably gonna put them in there final 3 gallon pot before flushing. I normally do 5-7 gallons but I just don't have the time currently to take care of plants that big plus I have about 200 more seeds easy.