well giving a universal answer to the question is always hard-
bbecause it depends in your setup, your condition, in the strain and vigourness of the plant, and so on-
just keep in mind that the leaves are the motor of the plant, they are pumping the fluids, and taking care of photosythesis
so back to you- i would go with the lower 30 Percent of the Plant, and take away small shoots and leaves
and depending in your training repeat it,
if you feel the plant has still to many shoots in the middle, get rid of them-
its like everything , you will find your own style, and what fits with your setup and conditions
when i started growing i tried one or 2 new techics in every grow, just o be sure its ok- and some decisions were good, and others not
but as always it depends in you and your style etc. there is like always no universal answer, you have to look at every plant
and give her , what she needs
in your case in wwek 3 of vegetation i just would go with taking away some leaves in the bottom area ( 3 or 4)
and doing some training line topping, to spread the canopy- as i have no clue because of no pictures, how your plant look like?-
its kinda hard to say anything