MrStinkyanswered grow question 3 years ago I know I have old eyes, and I dont want to panick you, but that could well be yellow leaf spot coming in - septoria. Keep a close eye and if you get a lot if pimples apprearing like the blemish in the darker leaf on the right in pic 1.
Either that or time to start feeding - is it on just a few leafs or on all leafs? Allmix should do up to about 6 weeks so now is about time to feed - hungry is more likely than septoria so treat for hunger first (as it is more gentle) and watch closely for developments.
With biobizz keep your doses low & constant every watering - you should notice sustained feeding of your soil microbes rather than a single dose per week will keep your rhizosphere pumping - I would also suggest topping up up your microbes when you add bb liquids to aid breakdowns of organic material as the vast majority of the nutritional content needs to be broken down to become available which will take a few days. If your plant is already hungry it is time to start feeding organics ASAP to avoid deficiencies developing.