I'm going to say it's definitely a calcium issue - but before you run off and grab the calmag, I've got to ask what your PH is... because it's going to be critical to your plant's ability to absorb the calcium. PH needs to be 6.0-6.3 to get the calcium in soil...
I'm also a little confused by your diary since it looks like you're giving them two doses of grow nutes and two doses of bloom nutes? Calcium can be locked out of a plant with too much nitrogen... With my grows (and I only grow autos), I start backing off the grow nutes at pre-flower and cut them out completely during the first week or two of flower. I add a different bloom nute - I have two that I use - one has NO nitrogen and one has a little and I will add this second one at the same time as I cut off the grow nutes but I will only start this second one off at 1/2 strength and increase it if the plant shows no signs of difficulty.
So my message is this: first, check the PH and make sure it's in a good range for calcium up-take, 2nd back off on any heavy nitrogen feeding (or cut it out completely), if neither of these things are an issue for your grow, then you can add some calmag to your feed - but ONLY ONCE A WEEK! And btw, those damaged leaves are never going to recover no matter what so you might want to trim them off. If you've solved the calcium issue, your plant will tell you by NOT showing any more of that yellowing and spotting...
Good luck!