Cheezyanswered grow question 5 years ago I haven't played with photoperiods yet but from all of my research you will be doing your plant a huge favour if you selectively defoliate.
Removing a couple every few days during veg will not negatively impact growth, it's best to remove the ones casting shadows on prime growth areas (side stems) and to remove leaves from dense areas.
You can also defoliate when changing the lights to 12/12, this is when growers will lollypop and remove ALL of the foliage from the lower 20% of the plant, including any branches you know won't yield much.
From here on you want to avoid stressing the plant with random defoliation so wait for 3 weeks. By this time there should be bud development, feel free to trim the big fan leaves casting any shadows onto bud sites. It is vital not to damage any bud sites!!
From here on out we are just watching the buds grow and ripen until harvest.
Growweedeasy.com is an amazing site full of great information on training your plants and diagnosing issues. https://www.growweedeasy.com/defoliation is where most of this information came from. Pigeons420 also defoliates with great success and even makes smoothies from the beautiful leaves his plants produce.
There is countless positive information on defoliation and because of that I know that when this method is implemented correctly you are guaranteed to improve yields. Defoliation can even help heighten the quality of lower buds due to the bud being able to receive the light to ripen.
My recommendation is to do some research and go for it! I snapped a stem in LST so mistakes will happen anywhere but these mistakes will lead us to learn better skills!
Happy growing bro🤙🤙