F1 is a science term, think s1 is less official like a few terms you'll see on "ethos" that sounds science-y but is not.
F1 is the first filial generation. You could think of it as the start of a family tree. Rather arbitrary where you start.
S1 means it's the first generation produced from a selfed plant. There are some other made up ones like R1 or Rbx etc. these are more like model numbers than real science terms.
I'm not a fan of selfed seeds. Even lower chance you find a plant that checks all the boxes fromt taste to yield to potency. the marijuana plant is quite sensitive to inbreeding, unlike some other types of plants. Even 1 generation has a noticeable impact. Last one i tried was grandpa's stash R1 and it was okay but also one of the worst plants of all that i grew last year. It was a "6" standing next to "8-9-10's" lol. And consitently, some amatuer F1s i made outpace and are frostier than the inbred shit.
https://en.
wikipedia.org/wiki/Mendelian_inheritance
https://biologydictionary.net/f1-generation/