I personally do not like doing any major defoliation after week 3 of flower.
The first few weeks of flower are what I consider a transition period, they can handle more stress with less consequences during this period.
You're now in full bloom so limiting stress is important IMO.
After week 3 I will still remove leaves but not as many at once, just a few here and there and only if needed for air flow.
I also only remove leaves that will be beneficial to remove.
Before I cut a leaf off, I'll move it by hand and see how much more light hits the plant and if it doesn't really help with light penetration then I won't cut it off.
Being you're in week 6, if you're having humidity and air flow issues then I would defoliate some for mold prevention.
If humidity and air flow are good and you only want to defoliate for light penetration, then I would remove smaller amounts of leaves and wait for plant to recover to remove more. Just be strategic in cutting your leaves off, make sure it's worth cutting it off before doing so like I mentioned before.
Clean your scissors with isopropyl alcohol before cutting, also before moving to another plant.