you are still not giving enough info.. are they autoflowers? If autoflowers,, the only concern is enough light and space...
If photoperiods, it's only fine if you intend to flower them all at the same time. You can't mix flower phase plants with vege phase plants... unless you want to take the flowering plants out every single day so tehy get their necessary 10+ hours of darkness to remain in flower. You definitely don't want to do that... forget once and it'll fuck those flowering plants up.
You switch to dehum when your humidifier stops running, lol... At some point the humidity created by teh plants will maintain it above your humidifier setting. If it continues to rise, you'll need the dehumidifier. This all depends on the your regional climate, size of the room, and size of the plants you grow.
I recently downsized slightly and now i barely need my dehum, which saves a ton of watts. Variables dictate need. There is no "one" answer. Life is rarely binary. It is a spectrum.