stem snap depends on size of stem. The only tricky part is that moisture evaporates off the surface of flower faster than it can traverse the plant material -- i.e. the interior has greater moisture than the surface. So, you just have to make sure it's actually dry after you seal it up to avoid major problems.
if you seal it up and it gets soft (a sign of greater moisture) on the surface again, you need to take it out. If you control the temp/rh, you'll gain familiarity. The density of buds varies, so you'll never be able to exactly predict, but you should be damn good at it after a few harvests. Be systematic and learn faster. Take notes about temps/rh and duraction of drying you gave it and whether you had to pull it out of containers or not etc.. you'll learn how long it typically takes and avoid much of the hassle after that.
Another way to know when it is at equilibrium with temp/rh is to weigh it. Have a representative bud of the typical size and density of your harvest and when it stops losing weight, you know it is at equilibrium with the temp/rh environment and is perfectly safe for long-term storage at that point.
2-way humidity packs give you room for error. They have a limit on how much moisture it can absorb or release, but gives you that buffer. Putting them in slightly early will correct itself. If drying temps and rh resulted in overly dry plant material, it'll provide moisture, too. 75-80% weight loss is normal.