Looks liek more of a genetics issue unless your coco is unbuffered / unwashed,. even then salt sickness would look different.
That vpd is a bit low for a mature or nearly mature plant. If that VPD is calculated based on air temp, then it's even lower than you think. I wouldn't go below .9 based on leaf temp (proper measurement of vpd). That can cause leaves to curl in on themselves, but the damage on the leaf shown could be mutation, or possibly something dripped on it as it formed but looks too spread out for that... I really dought a 1ec could cause serious damage, if anything it's slightly underfed.
irrigations habits are simple for coco coir - same as any other soilless medium. Coco is not magical and does not require any special treatment. If coco ever causes a problem in regard to calcium or anything else, it is poorly buffered, which is the manufacturer's fault or you bought unprocessed coco which is at least dangerous and can be lethal to plants. If you ever find inconsistencies with your coco coir product, buy a different brand next time.
Based on your description, it does sound like you are watering wrong. You don't pick the volume. you give what it takes to accomplish the task. unless that 250mL is enough to cause 10% runoff.. and allowing enough dryback for a healthy rootzone.
1) always fertigate with 10% runoff or more -- the runoff is essential
2) wait for appropriate dryback and repeat. With coco, when that top layer starts to change color, that's a healthy wet-dry cycle. You can trigger sooner, but i'd get thos roots properly grown before any increased fertigation.
In soilless/hydro symptoms are fixed through formula adjustment, since you provide 100% of nutrition. Runoff prevents buildup - a consistent level of nutes exist around the roots. Any leaf symptoms seen are fixed through the formula.. take notes. this stuff doesn't happen over night. it's a culmination of everything you do from day 1. feeding heavy early will required less later, for example. Check out dr. photons corner on cocoforcannabis.com. Best information based on facts and not anecdotale extrapolations of desperate people wanting to feel special because of their esoteric growing methods. Ther's no secret method with phenomonal results, lol.
So, if deviating from that, fix it.. could be a contributing cause. The plant pictured here looks like more of a genetics problem, but if new growth starts to look healthy, it'll grow out of it.
A good formula will work on 95% of plants. A lot of the perception that this plant is picky or difficult to grow is a matter of self-inflicted error and not looking in the mirror when things go wrong. With an indoor plant, kinda hard to blame anyone but ourselves when things go haywaire, lol. maybe, it was the boogey man? It couldn't be my overpriced fertilizer that's 'specially made for marijuana.' LOL
This may or may not fix things, but will allow for easier diagnosis once you eliminate caueses involving poor watering habits. pH swings can cause twsited growth, but if your pH is relatively steady, that's obviously not the case.