Recently I’ve came to an idea to defoliate slowly throughout the last weeks of growth when buds are almost done. Because I would have to trim the plant anyway so why not trim it while it’s growing so I don’t have to do it later and that way the plant would think it is being attacked and increase thc percentage as a defensive mechanism. You don’t lose nothing when you defoliate in last weeks like I said but if you do it in the vegetative stage with autoflowers it will definitely negatively affect your plants
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