Leaf strange

The yellowing means that your plant is hungry, it's nothing to be alarmed. Keep in mind that managing a deficiency is quite easy and it does impede flowering, just give it some grow nutes. unfortunately since biobizz is not too concentrated, you usually need much more than the recommended dose. What worries me are the spots on the leaves: is that water? because it looks like bugs. If it is water then nevermind, if it isn't, then get some neem oil and / or insectisidal soap.

Two things. You're low on nitrogen, this is causing the yellowing. The spots are coming from you misting the plants with water. The droplets magnify the lights and your leaf burns. Now, while I'm 99% sure about the second part, if you haven't been spraying the leaves, then you have pests, but I don't think that's the case. Add some nitrogen and stop spraying. Good luck!