DerekGRanswered grow question 4 years ago I'm by no means an expert, the opposite in fact but I have noticed similar spots on mine and every single time it was "water lensing" focusing the sun (i'm growing outdoors) and burning them. Nutrients will always burn the leaves if you are not careful while watering. In my case the yellowing never progressed beyond where it originally manifested and and I haven't had any new yellowing since I started paying the necessary attention to watering.
Are you sure it is not something leaf specific? If it's insects try looking underneath the leaf, this is where most insects leave their eggs not atop. Let us know how it progresses. Cheers!!! 😀