This is a magnesium deficiency, my friend, I think I answered this for you before, it starts off as a yellowing of the leaves between the veins. It then slowly starts to climb up the leaves and while it's climbing, some of the first affected leaves will develop rusty-looking spots. But don't get confused. The rusty-looking spots are actually a sign of calcium deficiency. When a plant is deficient in magnesium, it will also become deficient in calcium. Now as far as the BioBizz light mix, either there is something wrong with the soil which means contact BioBizz or your meter needs to be calibrated, if you calibrate the meter and still get the same ready, then the problem is the soil, if not then the problem is the meter.