Hi there, as long as all of your pistils are browned and opened then harvesting becomes a preference choice. The plant produces different cannabinoids and different stages of the flowering. As the flower ambers its CBD and CBN contents increase associated with a mellower body high. A very clear trichome is a heady high that can be unpleasant for many and can leave a bad hangover. A cloudy trichome has the highest THC content which slowly degrades with time as it does in the curing and jarring process. So when you harvest is a personal choice of how you would like to feel. If you are unsure perhapses harvest at different stages and try to find the clear/cloudy/amber ratio you like best. Happy harvesting!