defoliation

She seems to look strong, healthy and have plenty of growth to be able to handle the stress. Make sure to not do to much in one shot and a general rule to go off is clear everything from the bottom 1/3 of ths plant. As well as any large fan leaves covering a lot of undergrowth. These shouldnt stress the plant much at all if done in stages rather than all at once and will allow the plants energy to focus on bud production. Also the lower section cleared of leaves will add better airflow to reduce risk of any pest or mold issues once flowers start to chunk up. Congrats on getting to this point and best wishes for the future!!!

It's highly depending on your light, food, everything what we don't know ... Presuming it's my girl in my conditions I would take off those marked leaves, supercrop main stem thinking were to direct it ( better to most empty space) , give good support for it. Cleared all bottoms heavily for better air and quality of rest buds. https://ibb.co/vD7TTQ8 Flat canopy brings most results. Good luck !

strain is auto and she's 38 days...

need a little more info on her, but you could pull any leaves that block bud sites to start, depending on her age and strain auto? photo? Also remove any that point towards the center. it will open it up for air flow and light

Clean up some of the bottoms. Best of luck on your grow

She's pretty healthy man, you won't stress her. Just don't go too heavy. You can start from the bottom leaves, those in the shadow. Some people will say the leaves are the plant's engine (and it's true), but that mostly works outdoor. Indoor light won't penetrate more than about 40-50cm below the canopy. Good luck!