It COULD be lack of nitrogen, it COULD be just that it's one of the first leaves and they will tend to yellow-up and there's nothing amiss with that... the problem here is that you don't have a diary so we can't tell what it is you've been doing with this grow. Don't know the age, don't know the nutes, don't know the heat, don't know the humidity, don't know the light distance... If it's your first grow and you don't want to "mess it up" and you want advice that's worth anything, do start a diary so that when you ask a question, the community will have as MUCH information as possible in order to help you out!
Good luck, mate!