First time Grower Here :)

Im growing in 40cmx40cm with 3 plants,the plant is already stressed because of topping,topping is the most stressful technique for plants so its better to lst those big leaves and you can cut it later when the plant is recovers and is getting a lot bigger,you can lst with your hands or you can use whatever you think its soft and cannot damage the plant when you tie it up Good luck brother!!