Mold on my late-stage flowering cannabis

I would go with option 2, and make my room as dry as possible and start flushing immediately.

i have to deal with mold in my main colas rather often depending season weather strain and phenotypes within a strain. first remove all the moldy part from the plant as soon as possible then you can either try your luck pushing the plant a little bit more either harvest everything to prevent loosing more. keep in mind mold could continue to spread at the time of drying so inspect your buds carefully

cut off affected colas buddy look at your air exchange rate it needs to be increased a large outtake and a little bit of negative pressure is what your after :) best of luck buddy de humidfiers are a good bet too :)