Maybe?
VPD impacts rate of transpiration which impacts rate of drinking, and rate of drinking impacts your optimal concentration of fertilizer provided. (higher vpd = lower EC and vice versa). You shift one around, the others must jive with it or it'll be out of balance and you'll run into symtpoms within days-to-months. (closer to optimal, the longer it takes to see symptoms)
Is it better to adjust VPD or overall concentration of the nutrients provided? I am assuming you are in a soilless or hydro context if supplementing CO2.
Unless there's some reearch on it, you absolutely cannot trust the human eye on this and 10x so given a small numer of planys with varying genetics as your sample from which to draw conclusions. Just the fact of the matter. That doesnt mean someone won't be incredible confident about what they believe is true. Without real evidence to back it up be skeptical.
I'd stick to your typical VPD ranges for stage of life cycle and adjust your fertilizer formula as needed to avoid deficiencies or toxicities... dial it in until you find that goldielocks zone for vege / flower and whatever else for which you want to have a unique formula. I find 2 (vege and bloom) is enough, but YMMV.
You need temperatures at a higher range to maximize CO2 / rate of photosynthesis. When this stuff oscillates under normal conditions, people have traditionally adjusted fertilzier to match and not the other way around, but that doesn't mean it is 'best to do.' It might correlate, though.
In the end i doubt you can tell a different no matter what you choose to do. It all has to jive with growth... it's still a matter of observing and adjusting fert formula as needed.