I see no reason to defoliate. Can't see everything in this 1 picture, but it's easily explained.
Leaves overlapping or constantly touching the wall is an acceptable reason to selectively prune some leaves. Otherwise, there's not too many good reasons to remove a leaf. Try tucking/training before pruning.
You want to keep as many leaves as possible. Cutting them off does not 'allow the plant to focus on buds' or any other bro-science reasoning you may run across.
If your dehumidifier can't keep up with a full canopy you should either need more dehumidification power (an extra one or a stronger replacement) or you need to downsize your canopy relative to your equipments capabilities. If you don't have a dehumidifier, you better start growing in local seasons that have low humidity, if possible. Exhausting outside can help too, but this also raises cost of any heating/ac in your home..
if you remove leaves, you hinder yield. Leaves are lungs. CO2 is your limiting factor for photosynthesis potential of the plant, i.e. growth potential. Reducing leaf surface area reduces intake of CO2 which also reduces potential growth, which includes flower growth... anything the plant has to expend energy to do, it will be negatively impacted with fewer leaves.
It looks like you have removed some leaves at earlier points, likely too many. It's quite barren just below top portion of colas. That area receives strong light even if not at the top. You'd be better served if you retained those leaves in the future.
Despite a lot of ego-stroking techniques and urban myths, you'll realize 90-95% of potential, relative to the individual plant, by just doing the simple stuff well. Keep it healthy and the plant will do all the work.
check out cocoforcannabis.com -- "to defoliate or not..." is the first article you may want to read. All of their guides are good. You should read all of them as you can. you'll like re-read a couple, too. The author admits when they are making educated guesses and busts some myths. 'Dr. Photon's corner' as well as the guides and there's another site-authorized author of articles too, but i don't recall the name. The forums are just as riddled with bro-science as anywhere else, so beware of the user-submitted comments in the forums.