Low meq (milli-equivalents) in soil refers to a low Cation Exchange Capacity (CEC), meaning the soil has a reduced ability to hold positively charged nutrients.
Most people grow with low meq.
Think of it more like applying a template onto a medium, a template of minerals, because the soil doesn't have high meq it cant store many cations,
98% of minerals uptake through soil solution, 2% through soil particles, most soils are just moisture retainers for soil solution and not storage devices for soil particles.
Plant roots remove cations from the soil solution, which are then replaced by cations from the soil particles. But because you cannot store many cations, you need to apply a ratio or template of nutrients on a more consistent basis called fertilizers.
When to fertilize(apply template)? is based on EC level. Water, water, water till EC drops then re-apply the template onto the medium.