4th-5th week of flowering, right at the peak of this stage. But not after, need for nitrogen ceases.
You should use Cal-Mag during the vegetative and early bloom stages and during the halfway point of the flowering stage, you might want to reduce the application to 3 ml/gallon, to avoid adding a toxic level of nitrogen as nitrogen is the most sensitive to toxicity of all the minerals.
Calcium, magnesium, the grease on the wheels that makes everything work.