you have about 2-3 weeks left on this grow, the powdery mildew is just that a powder. you would be able to touch the area and you would have residue on your fingers, it is usually a greyish color but it is a dust like substance, you can take a clean paper towel and put rubbing alcohol on the paper towel and gently wipe the top and bottom with the paper towel and rubbing alcohol
this to me looks like a deficiency going on, or at lest from the pictures
you can cut the area away with out much stress un less that is a big bud that would ruin your harvest, looks to be a smaller one so it is up to you, she has a few weeks left and ask your self if you think you can fix it before harvest? other wise keep an eye on the area as well as looking at the whole plant. hope this helps