That entirely depends on what you want from your smoke... early harvest will give you a more cerebral high... waiting until the pistils are about 50% brown and the trichs are more milky than clear will give you a rounded cerebral-and-body high... late harvest, when the majority of the pistils have turned color and the trichs are more amber than not will give you couch lock - but beware that the later you delay harvest, the weaker the THC will be.
It's all in what YOU want...
Good luck!
Wait on the pistils to Brown more.Then check trichomes.If you cannot check trichomes with a microscope your best bet Is 3/4 Brown pistils or Just all Brown,but at this point you Could end up with more of a couchlock CBN effect than a cerebral THC effect.Depends on strain and phenotype