AsNoriuanswered grow question 2 years ago rusty spots are more ph issue first sign, which can lead then to calcium issues.
by picture, you are growing under led, i noticed that you have to use small amounts weekly, like 0.5ml/l once a week, does do good prevention.
other leaves are very healthy and not overfed, so its not nitrogen toxicity caused issues.
i would say you are safe if added a bit extra cal mag and make sure your ph is right and meter was calibrated.