Considering the early stage of development of your plant I would not defoliate as of now, as it looks more like nutrient issues to me tbh. Those could be caused by PH through nutrient lockout. Maybe. A fully vegged plant could get away with it more easily, matter of fact, I take all leaves which are blocking any of the smaller budsites, even on autos. When the plant has a "stable base" its not a problem at all, IMO.
In your place, Id tray to hold VPD relatively low, so you put least stress on your plant and try to (slowly) lower PH to around 6-6.2 range. You will see if it helps.
Keep it up!