Bro, if this is observed during the vegetative stage - it's a nitrogen deficiency, if it's at the beginning-middle of flowering then it looks like a cal-mag deficiency (not critical), but if it's on the lower leaves at the end of flowering - that's normal! From the photo, it’s clear that you've been in the flowering stage for a while, so everything is good, the plant is just borrowing missing elements from its lower leaves for its buds, those that are least illuminated and participate the least in photosynthesis! But if there's still a long way to go until the end of flowering as stated by the manufacturer, I recommend increasing the cal-mag concentration in your watering by 30%. Good luck bro! 👍