Continual cloning of the same plant will eventually lead to inferior plants, but this does take some time.
That is - growing a plant, cloning it, growing a plant, cloning it, growing a plant cloning it etc, etc, this can only be done so many times before the clones eventually lose vigour and potency.
But yes, new clones become new mother plants, as sooner or later, the original mother plants will need to be flowered or discarded.
Cheers, Organoman.