check pH... too little info.
looks like a boron def, but if you are in soil or using a proper hydro nute line for soilless, it is highly unlikely that you have a problem with trace elements, like boron.
so, without any info, probability dictates pH issue or lockout.
other possbility easy to eliminate. i've seen spots like that develop from light burn. are your lights too close? if unsure, judge by internode length on plant.. if they are too short, go ahead and raise light 2-4" and see if it stops. Those spots will never heal, but if it stops, you know that was the cause.