I'm using Exhale CO2 bags for the first time this grow. I have a CO2 meter and it's showing an increase of about 400ppm on average compared to fresh air. It's definitely making a difference, however it's also increasing my humidity more than I expected. They take a few weeks to get going and I believe they peak in output after about 3 months - I've had mine for about 3-4 weeks now so I think it'll still increase in output a bit more before it starts to die.
I am growing in a 4ft x 4ft tent inside a fairly well (but not completely) sealed room that is probably only itself about 8ft x 7ft in total. The tent exhausts straight out the top and into the same room. Even with the window open a few inches to stop condensation building up, the CO2 inside the tent is staying above 600 consistently, hits 800 regularly, and often reaches >1000ppm. I'm looking to get a dehumidifier to allow me to close the window and I suspect the CO2 bag will hit the higher numbers more regularly then.
It seems to work in cycles - like the plants aren't always expelling Oxygen, the fungus aren't always expelling CO2. But yes, it seems to be working as far as I can see. Any gains from CO2 are relatively minor though, and you have to have absolutely everything dialled in perfectly to take advantage of it, so I would make this the last thing you spend money on after you take care of everything else - lights, heat, airflow, nutrients, etc.
Good luck!