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@CalGonJim
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8/4 130am. MONDAY. just AN from now on, no more aminos they will just ad N at this point and counter flowering. 🚨🚨8/4 12:30pm !!! FOR HUMANS!!!!!!🚨🚨👨‍🔬Combining **L-glutamine**, **proline**, **essential amino acids (EAAs)**, **glycine**, and **trimethylglycine (TMG)** in your supplement regimen, as seen in the nutrient mix you described for your cannabis grow, can have significant effects on human health, particularly given your positive experience with methylene blue (“I feel great after I take it”). Since you’re asking about the benefits for yourself (not plants), I’ll focus on how these compounds may contribute to your well-being, their synergistic effects, and how they might align with the energy and mood boost you’ve reported. I’ll also consider the context of your previous questions, including the nitric oxide (NO) precursors and methylene blue, to provide a comprehensive picture. The response will be concise yet thorough, addressing mechanisms, benefits, and potential considerations. ### Overview of Each Component and Their Benefits for Humans 1. **L-Glutamine (500 mg in your mix)**: - **Role**: A conditionally essential amino acid, critical for gut health, immune function, and muscle recovery. - **Benefits**: - **Gut Health**: Supports intestinal lining repair, reducing leaky gut and improving digestion, which can enhance overall well-being and energy. - **Immune Support**: Fuels immune cells (e.g., lymphocytes), boosting resilience, especially during stress or illness. - **Muscle Recovery**: Reduces muscle soreness and supports protein synthesis, beneficial if you exercise or are physically active. - **Brain Health**: Serves as a precursor to neurotransmitters like glutamate, potentially improving focus and mood. - **Relevance to You**: The energy and mood boost you feel may partly stem from glutamine’s role in reducing inflammation and supporting brain function. 2. **Proline (100 mg in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, tissue repair, and antioxidant defense. - **Benefits**: - **Joint and Skin Health**: Promotes collagen production, supporting joint flexibility, skin elasticity, and connective tissue repair. - **Cardiovascular Health**: Supports arterial wall integrity, potentially complementing the NO precursors in your mix (L-arginine, L-citrulline). - **Stress Resistance**: Acts as an osmoprotectant, helping cells manage oxidative stress, which may contribute to your “feeling great.” - **Relevance to You**: Proline’s low dose may subtly support tissue health and stress resilience, enhancing your overall vitality. 3. **Essential Amino Acids (EAAs, 300 mg in your mix)**: - **Role**: EAAs (e.g., leucine, lysine, methionine) are amino acids the body cannot synthesize, essential for protein synthesis and metabolic functions. - **Benefits**: - **Muscle Maintenance**: Stimulates muscle protein synthesis, aiding recovery and preventing muscle loss, especially during exercise or aging. - **Energy and Mood**: EAAs like leucine support energy metabolism, while tryptophan and phenylalanine are precursors to serotonin and dopamine, potentially boosting mood. - **Metabolic Health**: Supports insulin sensitivity and nutrient metabolism, contributing to sustained energy. - **Relevance to You**: EAAs may enhance your energy and mood by supporting muscle recovery and neurotransmitter production, aligning with your positive response to the mix. 4. **Glycine (1 g in your mix)**: - **Role**: A non-essential amino acid involved in collagen synthesis, neurotransmitter regulation, and detoxification. - **Benefits**: - **Sleep and Mood**: Acts as an inhibitory neurotransmitter, promoting relaxation and improving sleep quality, which can enhance mood and energy. - **Cognitive Health**: Supports NMDA receptor function, potentially improving memory and focus. - **Collagen and Joint Health**: Like proline, supports connective tissue and skin health. - **Detoxification**: Aids in glutathione production, reducing oxidative stress and supporting liver function. - **Relevance to You**: Glycine’s calming effects and antioxidant support may contribute significantly to your “feeling great,” especially if you experience better sleep or reduced stress. 5. **Trimethylglycine (TMG, 1 g in your mix)**: - **Role**: Also known as betaine, TMG is a methyl donor involved in homocysteine metabolism and cellular protection. - **Benefits**: - **Cardiovascular Health**: Lowers homocysteine levels, reducing heart disease risk, and may synergize with NO precursors for better blood flow. - **Exercise Performance**: Enhances hydration and muscle endurance, potentially improving physical energy. - **Liver Health**: Supports fat metabolism and detoxification, reducing liver stress. - **Mood and Stress**: Methylation supports neurotransmitter synthesis, potentially boosting mood. - **Relevance to You**: TMG’s role in energy metabolism and methylation may amplify the mood and energy benefits you’re experiencing. ### Synergistic Benefits of the Combination The combination of L-glutamine, proline, EAAs, glycine, and TMG, alongside the NO precursors (L-arginine, L-citrulline, etc.) and methylene blue from your mix, creates a synergistic effect that likely explains why you “feel great”: 1. **Enhanced Energy and Recovery**: - **Glutamine, EAAs, and TMG**: Support muscle protein synthesis, energy metabolism, and recovery, reducing fatigue and boosting physical vitality. Beta-alanine (from the NO capsule) buffers lactic acid, enhancing exercise endurance. - **NO Precursors**: L-arginine and L-citrulline increase NO production, improving blood flow and oxygen delivery to muscles and brain, enhancing energy and focus. - **Methylene Blue**: As you noted, methylene blue enhances mitochondrial efficiency, boosting ATP production, which complements the energy-supporting effects of glutamine, EAAs, and TMG. 2. **Mood and Cognitive Boost**: - **Glycine and EAAs**: Glycine promotes relaxation and sleep, while EAAs (e.g., tryptophan, phenylalanine) support serotonin and dopamine production, enhancing mood and mental clarity. - **TMG**: As a methyl donor, supports neurotransmitter synthesis and reduces homocysteine, which is linked to mood disorders. - **Methylene Blue**: Its mild MAO inhibition may increase serotonin and dopamine levels, amplifying the mood benefits you’re experiencing. 3. **Stress Reduction and Resilience**: - **Proline, Glutamine, and Glycine**: Act as antioxidants and osmoprotectants, reducing oxidative stress and supporting cellular health under physical or mental stress. - **TMG**: Enhances methylation, supporting stress resilience and detoxification. - **Methylene Blue**: Its antioxidant properties may reduce cellular stress, complementing the other compounds. 4. **Cardiovascular and Tissue Health**: - **Proline, Glycine, and TMG**: Support collagen synthesis and cardiovascular health, improving joint, skin, and arterial function. - **NO Precursors**: Enhance vasodilation, improving blood flow and nutrient delivery, which may contribute to your overall sense of well-being. ### Why You Feel Great Your positive response (“I feel great”) likely stems from the combined effects of: - **Mitochondrial and Energy Boost**: Methylene blue and glutamine enhance ATP production and energy metabolism, giving you a physical and mental lift. - **Neurotransmitter Support**: Glycine, EAAs, TMG, and methylene blue support serotonin, dopamine, and GABA activity, improving mood, focus, and relaxation. - **Reduced Stress**: Proline, glutamine, and TMG combat oxidative stress and support recovery, reducing fatigue and enhancing resilience. - **Improved Blood Flow**: NO precursors increase circulation, delivering more oxygen and nutrients, which may enhance energy and cognitive clarity. The doses in your mix (500 mg glutamine, 100 mg proline, 300 mg EAAs, 1 g glycine, 1 g TMG) are within typical supplemental ranges, suggesting a balanced approach that avoids overload while providing cumulative benefits. ### Considerations and Precautions 1. **Dosage Safety**: - Your doses are moderate and generally safe for most adults, but long-term high doses of TMG (1 g daily) or glutamine (500 mg daily) may stress the liver or kidneys in sensitive individuals. Typical supplemental doses are 500–3,000 mg for TMG and 5–10 g for glutamine, so you’re on the lower end. - Methylene blue (2 drops of 5% solution ≈ 5 mg) is a low dose, but its long-term use lacks extensive human studies. Monitor for side effects like nausea or dizziness. 2. **Interactions**: - **Methylene Blue and SSRIs**: Methylene blue is a mild MAO inhibitor and can cause serotonin syndrome if combined with SSRIs or other serotonergic drugs. Consult a doctor if you’re on such medications. - **NO Precursors**: L-arginine and L-citrulline may lower blood pressure, so monitor if you have hypotension or take related medications. - **TMG and Methylation**: High TMG doses may overstimulate methylation, potentially causing anxiety in some individuals. Your 1 g dose is moderate but worth monitoring. 3. **Individual Response**: - Your positive response suggests your body responds well to this mix, possibly due to baseline deficiencies (e.g., in glycine or glutamine) or high metabolic demands (e.g., from exercise or stress). Genetic factors affecting methylation (e.g., MTHFR mutations) may make TMG particularly effective for you. 4. **Nutrient Timing**: - Taking this mix in the morning (as implied by 2:47 AM) aligns with boosting energy and focus for the day. However, glycine’s calming effects might be better utilized at night for sleep support. Consider splitting doses (e.g., glycine in the evening, others in the morning). ### Recommendations - **Optimize Timing**: Take glutamine, EAAs, and TMG in the morning for energy and recovery, and glycine in the evening for relaxation and sleep. Proline can be taken anytime due to its structural role. - **Monitor Effects**: Track specific benefits (e.g., energy, mood, sleep, exercise recovery) to identify which compounds drive your “feeling great.” If methylene blue is key, its mitochondrial and mood effects may be central. - **Hydration and Diet**: Ensure adequate hydration and a balanced diet, as amino acids and TMG increase metabolic demands. Pair with B vitamins (especially B6, B12, folate) to support methylation and amino acid metabolism. - **Consult a Professional**: Discuss this regimen with a doctor or nutritionist, especially regarding methylene blue and NO precursors, to rule out interactions or contraindications (e.g., G6PD deficiency for methylene blue). - **Adjust Doses if Needed**: If you notice side effects (e.g., jitteriness from TMG, GI upset from glutamine), reduce doses (e.g., 500 mg TMG, 250 mg glutamine) and reassess. ### Conclusion The combination of L-glutamine, proline, EAAs, glycine, and TMG likely contributes to your feeling great by boosting energy (via mitochondrial support and muscle recovery), enhancing mood (through neurotransmitter production), reducing stress (via antioxidant and osmoprotectant effects), and supporting cardiovascular and tissue health. Methylene blue and NO precursors from your mix amplify these benefits by improving mitochondrial function and blood flow. Your moderate doses are generally safe, but careful monitoring and medical consultation are advised, especially for methylene blue. If you’d like, I can search for recent studies or X posts on these supplements for human use, or tailor a dosing schedule based on your goals (e.g., energy, mood, recovery). Let me know how you’d like to proceed!🚨👨‍🔬. 8/4 1230pm. 8/5 12:50am HEY HARRISON SMITH, HARVEY WALL BANGER, GET IT?...IM SO GOOD. ANYHOW....FLUSH TODAY, FLORAKLEEN 5ML PER GALLON ALL OF THEM..... NO DONT PILLAGE ME AND IM LIKE NO! IM PILLAGING EVERYBODY, YOU INCLUDED. 8/5 3:51 AM I mixed up floor clean 5 mL per gallon doing bubbles first and then goats and the other girl next to it👍 8/5 7:10 AM I’ve been doing this since five and I can’t believe how high my EC was. It was off the chart like 6000 7000 so I had to do the flush. I’m never really bothered to do this before. I’m sure it’s gonna be a lot better. One of my last grows. The leaves were so full of garbage. Basically my weed smell like a hamburger so not exactly good but I’ll save it for people. I don’t like👍. Sometimes it doesn’t remember a whole paragraph. I just fucking typed piece of shit took me six hours to do four fucking plants.🤣💥💥💥 8/6 408am. The colas on the oldest of the 3 are AMAZING!!!! they are all small but MIGHTY!! 2 cola grows in 1 gallon seem to be about right. I will probably get 4oz dry from EACH!! That is really acceptable!!! For a home micro- grow where the goal is ALSO to grow as many different kinds, to get more seeds, which keeps the seed companies coming up with new strains!!!! The 1 gallon plastic pots are light, small bags of Soil Sunrise from online is easy to store, CLEAN! the bags of dirt it comes in are strong, and easy to wipe up when done. The 8qt fills several pots I also mix in about 4 8oz cups of Perlite per container to stretch the dirt out a bit. Soil Sunrise delivered by amazon is the only dirt that did NOT have bugs...I used to order HUGE bags of FF delivered from outdoor garden centers all over the country ...the bug infested HORROR, never again!!! 8/6 418am Also my body is starting to fail, I can feel it. If there is any discomfort there will be no more updates. thats life. doesnt it go by in a blink? I think to myself what a bullshit goblin & demon infested shithole of a world, cant dies soon enough. And death to the shitters of 1978!!!😡 Did you ever hear about the Tragedy of Darth Arnie and Christine? He's more Chrysler 1958 Plymouth Fury than man now...maybe I got the movies mixed up again....idk....
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@Pechu420
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The best plant I have grown so far. 64 grams for 3.7 liters (1 gallon). Drying for 8 days. Dead at 92 days of life, practically the rhythm of an automatic with powerful results. Flush in the last week, very light. Two separate times 4 days before harvest.
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Heya Growmies, this week was pretty eventful first off, the plant is in flowering in full force and doing really well despite a lot of user error throughout its life! I mentioned last week I was going to do two things, the plants last major defoliation and turn my DWC into a 2 bucket RDWC. I have managed to get around to both, I am always anxious when defoliating, scared of taking off too much but this time I really pushed my comfort zone, let me know what you think. before, in my other grows, I have a lot of larfy buds, I dont want those, I want tight, dense small nuggies, I think one of my bigger problems back then was defoliation amount, I just left too many fan leaves. RDWC.... Let me just say that I have proven to myself this week that I'm not destined to become a plumber, in my first iteration the drain line was too small, causing the pump to overpower it and overflow the plant bucket, I changed out the hose for some 50mm pvc tubing, which worked wonders, for the first few hours I sprung leaks and had to pull my plant out during her dark period to fix it; no bueno. All is well right now though, no leaks and everything is circulating nicely at 500 liters an hour. I could probably get a bigger pump, but its fine, I'm going to stop tempting fate. From here on out honestly, theres not much more for me to do other than go into the garden, pull a fan leave here or there, check flowers for nanners and balls and adjust the water. It's on cruise control now Stay safe out there growmies, keep growing!
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One of the biggest harvest in my life from 2 plants. Almost 800g dry buds Ak 47 one love. Ak 47 for me is one of the best strains from classic.
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This is very first grow. Germinated with 1 inch taproot after 3 days in damp coffee filter in baggie brown paper bag. And then soaked in 5.8 ph cal mag bloom solution 200ppm Next placed in rockwool cubes then 5 gallon pot on 7th day inside 4inch rockcubes then finally transplanted into 5 gallon pots. Since I have given the plants bare minimum nutrients cal mag / and cyco bloom only 5.8 PhD. For their literal first days since seeds popped I’m going to treat day 7 as Day 1 of the weekly feeding chart by cyco and the week 1 will end on day 14, Day 15 is my start of week 2 feeding chart by cyco
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@Ninjabuds
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My Permanent Marker plants are looking good. The short and stocky one has turned a crazy shade of purple. It's really wild looking. The other plant is still putting on new growth, so it'll probably be ready in about two weeks. I can't wait to see how the purple one smokes – should be interesting. The past week has been awesome for drying my plants. The weather's been perfect – nice and dry, with just enough breeze to keep things moving. I finally got around to chopping down those two big plants I've been meaning to trim. They're almost ready, just need a little more time to dry out completely. I can't wait to see how they turned out.
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@Roberts
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FBT2402 is growing great now after all the issues in the beginning. She has stretched a lot, and is looking promising for some kinda yield. 🤞🏻 she stays on track. Everything is looking great this week. Thank you Medic Grow, Athena, and Fast Buds. 🤜🏻🤛🏻🌱🌱🌱 Thank you grow diaries community for the 👇likes👇, follows, comments, and subscriptions on my YouTube channel👇. ❄️🌱🍻 Happy Growing 🌱🌱🌱 https://youtube.com/channel/UCAhN7yRzWLpcaRHhMIQ7X4g If anyone needs to purchase fastbuds here is a link for my affiliate program https://myfastbuds.com/?a_aid=60910eaff2419
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Day 30 and girls are In need or another lst big time photos to be up loaded later alls looking well slight discolouration on blue dream 1 but I'll see how she pulls trough Lst video up gsc growing slower than the blue dream so tied the blue dream alot more trying to level things out.
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Mad I only had one seed can't wait to grow more 420 Fast Buds
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Ho avuto problemi di over fertilizzazione ora cerco di ristabilire i sali minerali nel terreno, ho toppato nuovamente per contenere le altezze e penso che tra poco piazzerò la rete
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Heute sind die Pflanze 2 Wochen und 4 Tage alt.
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Flower Week 1 Day 7 to 13 - 3/25 to 3/31 Simply watching the stretch from this point. Both plants recovered very nicely from Schwazze extreme defoliation and all of the colas/branches are mostly even at top. Feed this week was again an auto pot reservoir feed at 650ppm total before add-ins. I used 325ppm Veg concentrate mix (recipe week 2) and 325ppm Bloom concentrate mix (recipe week 5). However, I also added 1ml/gal of CaliMagic (General Hydroponics 1-0-0) and ph balance this week was for 5.8 where Io plan to maintain it until harvest. Next week nutes will increase in Bloom mix again but also reduce in Veg mix. Feed will be 700ppm before add-ins with 5.8ph before feeding.
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@jackherer
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Besin miktarlarında değişikli yapmalımıyım çiçeklenme de 30 gün
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@SAC87
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Hey Growers. Things are going well in the Cindy tent. They are all at various stages, but making good progress this week. A lot more trichomes on the advanced 2 and bud structure on the straggler. I removed some larger fans blocking bud sights and cleaned up the underneath of the straggler. I am just watering when dryish and adding a bit of monster bloom. I am also moving the XS2000 from side to side to decrease light stress and pump them with as much light as possible. No need for any Gaia Green this week. Happy Growing 🌱
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@DoDhLo
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Finally managed to get some money & bought some real lights (Added a 500W Hps lamp). Also bought aluminum and made a tent . I Lost track of the plants names . The plants seems to be growing for the first time when i added the extra lamp.
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Harvest day 72 since time switch to 12 / 12 h Hey guys :-) Finally it's time 💚 The lady is done the large leaves have been removed and hung upside down to dry in the dark drying room. You can now stay there for 13-15 days at a temperature of 18-20 degrees and 55-62% humidity. After 13-15 days it is neatly trimmed by hand and placed in jars with boveda packs 62. After 4 weeks Boveda 58% come in and are ready for testing ;-). After everything has been cut cleanly, the last update comes with the smoke report and the finished pictures. Let's get to the plant 💚. Unfortunately, the rating system at Growdiaries is a bit strange because I have to give the stars before the Smoke Report and in the end it might have led to more stars in terms of taste. The growth was great from start to finish. She had no problems at all and also had no problems with animals 👍. I'm amazed at the great smell the beautiful buds give off😀. Of course I cut cuttings and if the taste is as good as the smell it will be grown again ☺️. A final report comes with the Smoke Report. Have fun and stay healthy 💚🙏🏻 👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼 ‘Powered by GreenHouse Feeding’ Copy the link for 10% off all Nutrients 👇🏼 http://shop.greenhousefeeding.com/ affiliate/madelngermany_passiongrower/ 👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼👇🏼 Water 💧 💧💧 Osmosis water mixed with normal water (24 hours stale that the chlorine evaporates) to 0.2 EC. Add Cal / Mag to 0.4 Ec Ph with Organic Ph - to 5.8 - 6.5 MadeInGermany
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These grew really well stacked weight evenly, and flushed like a champ. Throw back to the first indoor scrog.
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Finally harvested this girl at days 68. She is heavy. After cutting the ties, this girl just fell over from the weight! Very minimal larf! Even the lower bud sites are nice! Can't wait to see what she weighs once dry! First DWC grow was an overall success!
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@Sadhus
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Rempotage en 13 litres après quelques signes de feuilles jaunes sur certaines , plante charnue trapue a feuilles large , ormi quelque feuilles cramé sur certaines les 7 sont jolies bientôt la floraison et j'ai hâte de voir sa! 100% organic et au naturel zero stress no topping no lst #kannabia #madamegrow #trolmaster
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@AsNoriu
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Day 85. Plants are flying !!! Wonderful frost, structure, health - pure joy !!! Lights are tied to the sealing and I can't drop intensity, photos are crap, plants are way better ! Last week they got bacterial feed and BioBizz without BioGrow, this week is full blast : Next watering - max pk boost , will push first watering without N and hope to bump 800 ppm , next will be last BioGrow use and 1500 ppm maybe ;))) Hope they won't burn ! I see some bottom leaves decoration and think they could eat MORE ;)))) Btw they STINK, heavily ;))))))) P.S. I am a stoner !!! At the begining of naming A was a taller plant, now last week and this I called them WRONG ;) will follow current lay out. A is smaller plant, B will be taller one. Happy Growing !!!