You need to know what you feed to make an educated guess here -- even then it is still a guess, butnot a blind stab in the dark.
toxicities and out of balance ratios of nutrients can cause any and all symtpoms.. and adding the wrong thing only makes it worse. if not armed with this knowledge, you can't do anything useful that isn't pure luck.
calculate from your labels ppms (molarity is better, but no one uses it for comparison reasons, stick to unsophisticated ppm) of what you feed.. google a bit (e.g. rollitup has some nutrient fomrulas of various brands in a nice post). Get an idea of what is normal.)
if you provide plenty of Ca, it's clearly something else... if not, you know to stick with it. It won't heal in a matter of days. Ca and Mg take upto 4-6 weeks just to show symptoms from onset of problem. Those rust spots don't heal, if i recall.