Athosanswered grow question 6 years ago No set time, since it depends on what you are trying to do. Most do it around the 5th node. I would advice you to wait until the plants has 5 nodes, to give it time for the roots to develop and so it can recover quicker (even if you top back to the 1st or 2nd node). Try to get 4 tops per sq ft as a starting point. Hope that helps.