Is that the only branch doing that? It looks like variegation starting to me. I've had it in several strains where a side shoot would just spit half good half weird splotchy leaves. If it isn't spreading and not on other areas of the plant its probably genetic mutation. Nothing you can do about it, if that bud is going to be tiny anyway you can just cut it off so more energy to good nodes.
Look up cannabis variegation all sorts of weird things can happen when breeding seeds. I can't attach a pic but I've had a bud that was split right down the middle like that, weird on one side, symmetric and green on the other.