bio bizz instructions must be useless, lol. see a lot of questions invovling them and messed up canopies.
i'd second the 'overfed' vote, too. Might even be locking something out, because there's more than 1 type of symptom going on. Check pH too.. but need to see how this progressed and make a more informed decision. When it's a smorgasborg of symptoms, reading leaf symptoms is even futher from discrete than normal. Balance could be off with some stuff too high and too low, too.
soilless is easy peasy.
a ratio and concentration of nutes that will work well and require minimal adjustments:
N 120-130
P 50-60
K 180-190
Ca 100+ (depends on tap water a bit)
Mg 75ish (depends on tap water)
S 100-110
This is a light concentration that is safe to start with. A free phone app can take the percents from guaranteed labels on fertilizers and convert to ppm. there are internet calculators that cna do that for you too, so no heavy lifting needed. If deviating greatly from these numbers, good chance that is where the problem lies.
In flower, you may want N ppm near 110 or so. A little lower, but nothing too drastic.
6.0 ph +/- 0.2 is fine.. hell even 6.5 can work. You'll probably get measurably more production with slightly more acidic than 6.5, but it is not something you can see with your eye as far as scale of that effect.