If you decide to defoliate, just go with a few leaves she ain’t the bushiest. Here is some information about this subject, im doing it for years with this tutorial: https://www.growweedeasy.com/nebulas-super-simple-3-step-defoliation-tutorial
If defoliate and how much always depends on how the plant is growning.
Id remove only leaves that cover budsites and leaves and buds that are so low that they don’t receive much light and would not produce in the end. If you start with defoliation go slow first, learn how plants react. This can be also different with each genotype/phenotype they all take the stress differently. After week 3-4 you don’t want to put much stress on your plants anymore, since they should concentrate on flower production/bulking week 4-7. if you decide to defoliate at this stage only take single leaves at a time