Yellow marks middle of the leaves and curls down

Looks like the autos went into shock and flowered early. If you topped them, don't only LST for autos. They are little bitches with stress. at least from my exerence with em.

Reminds more of ph issue and troubles from that .. Btw do you use tap water ? It has loads of chlorines, that could influence a lot ! Fish mix is very potent, i kicked it out ftom feeding after many good and bad attempts, bio grow alone does the thing too. Used biobizz for 4 years and always loved that line. They are not overfed with nittogen, but, some calcium signs ( like patching around leaf veins ) could speak about calcium toxicity, but normally biobizz calmag is weak, not stable too, you get more deficiencies , than toxicity from it.

1st - Ca excess 2nd - Mg stop using ur CalMag fert for a week or 2 then cut in half the dosage bs u're overfeeding em and cause lockouts or u can keep feeding em and u'll what u get _

Hey 👋 Guess yan already mentioned most of the possible issues. If you fed her hard in the beginning your curling leaves can also show overfeeding with nitrogen… in my opinion BioBizz Grow is too hard. Too much nitrogen can also lead to slower growth, which possibly explains why you plant is pretty tiny for 6 weeks. Also your leaves look a little dark green. Hope that helped 👊🖖🍀

Hey growmie, I deleted my previous answer, didn’t notice the perlite before (duh lol), so scratch the compaction talk. They’re definitely small for 6 weeks. The yellowing looks like early magnesium or sulfur deficiency, maybe some pH lockout. Curling and droop could be overwatering or stressed roots. Allmix is strong on its own, so adding full Biobizz feed early can sometimes overdo it. I’d ease off a bit, let the soil dry more between waterings, and keep pH around 6.2–6.5, you’re not far off, they just need time and a gentler rhythm. Should bounce back ✌️🤞🍀♥️