It’s beyond doubt that cannabis is a mood-altering substance, and it’s only natural that many people use it for bipolar disorder, a condition characterized by violent mood swings. Whether it’s ups or downs you’re experiencing, smoking some weed will definitely affect the way you feel, but it’s hard to predict how. Some patients report cannabis has helped with their bipolar disorder symptoms, others say it makes them worse, so always make sure to consult your doctor and be very watchful of how medical marijuana affects you. In some cases, it may really ease the symptoms of bipolar depression, increase motivation, replenish energy, and provide more focus in the depressive phase, or conversely, calm you down and make you sleep better in the manic phase. Or not. The low-THC, high-CBD strains are probably a safer alternative to potent varieties, but our list of the best strains for bipolar disorder contains them all and is based on anecdotal reports from medical-marijuana users.