Ok, you asked about defoliation... I don't happen to think it's necessary at all at the moment... and it may NEVER be necessary. If you're concerned right now, you could simply take those large fan leaves and tuck them under the bud sites that they may be shading.
You want to do defoliation for a REASON... either to get more air flow into your plant or to get more light to the lower portions of your plant. At the moment, the best way to do the latter would be to do some LST... if you have any questions at all, please go to my profile and click the chat button - I'd be happy to talk to you...
Nice looking grow, btw!
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