Hello Dr Mambo,
it all depends, you can get a lot of different answers.
Personally, I would just do a light defoliation. To allow better light access to the inside of your canopy. I would also do LST to help your secondary branches develop.
Best wishes for this year 2021 with lots of flowers and greenery.
👉🤩🌿🌱🎋👨🌾😁😁