if it is mostly where a stem is exposed to light, could be LED... nothing you can do here
can also be a deficiency in P deficiency if only the petioles..
can also be a Sulfur deficiency if long streaks in stems.
and on top of all that could be locked out by something elses or pH...
so, use what info you have and eliminate possibilities. Magnesium Sulfate is an option to add S, but need to consider how much Mg you already provide too. It's worth while in these cases to know what you feed per molecule in PPM. A little spreadsheet can haelp autocalculate such things as you change your dosage fields. manic botanix also has an online calculator.
if a formula doesn't work well for 80-95% of strains, it's not a good formual, imho. only minor adjustments should ever be necessary except for oddball plants that are fairly rare in the first 100+ plants i've grown. Not sure if i had one that required anything drastically different at all.