Yes, you can . With everything how you do something is what’s key. Selectively defoliate only what’s blocking primary bud sites, lst “low stress train branches outwards by gently making the branch pliable then stretch & pin down the branch. It will widen your plant giving better air flow & light penetration. You want your leaves as many as reasonable they are a food source as are the roots. I’
I’d try to be finished bending branches & doing any heavy major defoliating by mid week 2 flowering. From that point onwards I’d let her ride pampering her only selectively defoliating as necessary & with healthy growth that’d be every other week so probably perhaps once more after week 2 flower then leave her & the rest alone until trimming BUT again I’d only remove selectively as NECESSARY to accomplish uniform bud structure & air flow